Kajian Dendrimer (Poly)Amidoamine (Pamam) Generasi 4 Sebagai Template Dalam Pembentukan Nanopartikel Secara In Silico

Content Provider	Semantic Scholar
Author	Sastyarina, Yurika Nafisah, Zuhrotun Yusuf, Muhammad Mutalib, Abdul Soedjanaatmadja, Ukun M. S. Ramli, Martalena
Copyright Year	2017
Abstract	Dendrimers are a class of highly branched synthetic polymers that has spherical form consist of three components: core, branch and terminal functional groups. One of dendrimer that has been commercialized is (Poly)amidoamine (PAMAM). PAMAM dendrimer used as a template in the preparation of gold nanoparticles. This research was studied the streched cavities of (Poly)amidoamine (PAMAM) dendrimer generation 4 using in silico method. Structure of (Poly) amidoamine (PAMAM) dendrimers generation 4 downloaded from Building Toolkit (DBT) Library and before the simulation structure was prepared. Then molecular dynamics simulations run using the AMBER program at 37°C in aqueous conditions. From analysis, obtained that the furthest distance of streched cavities at the closest distance from the core, region between residues 2 and 3 is 23.696 A… and at the terminal region between residues 100 and 122 is 58.045 A…
Starting Page	35
Ending Page	42
Page Count	8
File Format	PDF HTM / HTML
DOI	10.25026/jtpc.v4i1.130
Volume Number	4
Alternate Webpage(s)	https://jtpc.farmasi.unmul.ac.id/index.php/jtpc/article/download/130/129
Alternate Webpage(s)	https://doi.org/10.25026/jtpc.v4i1.130
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article