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Glucosylated caffeoylquinic acid derivatives from the flower buds of Lonicera japonica
| Content Provider | Semantic Scholar |
|---|---|
| Author | Yu, Yang Jiang, Zhibo Song, Weixia Yang, Yongchun Li, Yuhuan Jiang, Jiandong Shi, Jiangong |
| Copyright Year | 2015 |
| Abstract | Three new glucosylated caffeoylquinic acid isomers (1-3), along with six known compounds, have been isolated from an aqueous extract of the flower buds of Lonicera japonica. Structures of the new compounds were determined by spectroscopic and chemical methods as (-)-4-O-(4-O-β-d-glucopyranosylcaffeoyl)quinic acid (1), (-)-3-O-(4-O-β-d-glucopyranosylcaffeoyl)quinic acid (2), and (-)-5-O-(4-O-β-d-glucopyranosylcaffeoyl)quinic acid (3), respectively. In the preliminary in vitro assays, two known compounds methyl caffeate and 2'-O-methyladenosine showed inhibitory activity against Coxsackie virus B3 with IC50 values of 3.70 μmol/L and 6.41 μmol/L and SI values of 7.8 and 12.1, respectively. |
| Starting Page | 210 |
| Ending Page | 214 |
| Page Count | 5 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.apsb.2015.01.012 |
| Alternate Webpage(s) | http://ftp.ncbi.nlm.nih.gov/pub/pmc/d2/dc/main.PMC4629231.pdf |
| Alternate Webpage(s) | https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d2/dc/main.PMC4629231.pdf |
| PubMed reference number | 26579448 |
| Alternate Webpage(s) | https://doi.org/10.1016/j.apsb.2015.01.012 |
| Journal | Medline |
| Volume Number | 5 |
| Journal | Acta pharmaceutica Sinica. B |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
