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New Polymeric Ion Selective Electrode for Determination of Sulfamethoxazole in Pure and Pharmaceutical Samples
| Content Provider | Semantic Scholar |
|---|---|
| Author | Abrahem, Sarra A. Al-Saidi, Khaleda H. |
| Copyright Year | 2015 |
| Abstract | Sulfamethoxazole ion selective electrodes were constructed based on sulfamethoxazole - tengestophosphoric acid as ion pair complex in a polyvinylchloride matrix and plasticized by four plasticizers, Di-octyl phthalate (DOPH); Tri-butyl phosphate (TBP); Acetophenone (AP) and Nitrobenzene (NB). Sulfamethoxazole electrodes (E1, E2, E3 and E4) gave slopes (52.008, 58.381, 56.909 and 50.309 mV/decade) and linear ranges from (1×10-5-1×10-2,1×10-7-1×10-2,1×10-5-1×10-2 and 1×10-5-1×10-2 M) respectively. The best electrode (E2) was based on TBP plasticizer which gave a slope 58.381mV/decade, correlation coefficient 0.9997, detection limit of 9×10-8 M, lifetime 27 day. pH and life time of the electrodes were also studied and the proposed electrode displayed a good stability and reproducibility and were used to determine the Sulfamethoxazole in pharmaceutical samples. The interferences measurements in the presence of (Na+, K+, Cu+2, Mn+2, Fe+3, Al+3, trimethoprim, starch, sucrose and gelatin) were studied using the separated method and mixed method for selectivity coefficient determination. |
| Starting Page | 25 |
| Ending Page | 32 |
| Page Count | 8 |
| File Format | PDF HTM / HTML |
| DOI | 10.22401/jnus.18.2.04 |
| Alternate Webpage(s) | https://www.iasj.net/iasj?aId=102075&func=fulltext |
| Alternate Webpage(s) | https://doi.org/10.22401/jnus.18.2.04 |
| Volume Number | 18 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
