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Facile synthesis of nonsymmetrical heteroaryl-substituted triarylmethanes via the FeCl3·6H2O-catalyzed two-step Friedel-Crafts-type reaction.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Ruengsangtongkul, Sureeporn Taprasert, P. Sirion, Uthaiwan Jaratjaroonphong, Jaray |
| Copyright Year | 2016 |
| Abstract | The FeCl3·6H2O-catalyzed three-component aza-Friedel-Crafts reaction of aromatic/heteroaromatic compounds, aromatic aldehydes and tert-butyl carbamate was reported. The subsequent Friedel-Crafts-type alkylation of the resulting tert-butyl diarylmethyl carbamate with heteroaromatic compounds under "open-flask" at room temperature was also performed. The two-step reaction was especially useful for the synthesis of functionalized nonsymmetrical heteroaryl-substituted triarylmethanes in good yields under an air atmosphere at room temperature. |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/c6ob01638c |
| PubMed reference number | 27541849 |
| Journal | Medline |
| Volume Number | 14 |
| Issue Number | 36 |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/c6/ob/c6ob01638c/c6ob01638c1.pdf |
| Alternate Webpage(s) | https://doi.org/10.1039/c6ob01638c |
| Journal | Organic & biomolecular chemistry |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |