NDLI: Inhibitory Effect of Fluconazole Combined with Amphotericin B on Fluconazole-Resistant Candida albicans Biofilm Formation

Content Provider	Semantic Scholar
Author	Neamati, Sara Khodavandi, Alireza Alizadeh, Fahimeh
Copyright Year	2019
Abstract	Materials & Methods: Fluconazole-resistant C. albicans was identified among colonized clinical isolates of C. albicans obtained from the patients at Shahid Beheshti Hospital, Yasooj, Iran, between September 2016 and January 2017. The MICs of fluconazole alone and in combination with amphotericin B were determined on fluconazole-resistant C. albicans by broth microdilution method based on the CLSI document M27-A3 and the synergistic effects were interpreted by the FIC index. To address the inhibitory effects of drug combinations, we investigated the anti-biofilm activities of fluconazole alone and in combination with amphotericin B against fluconazole-resistant C. albicans using crystal violet staining, light field microscopy and expression analysis of HWP1 using RT-PCR.
Starting Page	1
Ending Page	8
Page Count	8
File Format	PDF HTM / HTML
DOI	10.30699/jambs.27.122.1
Volume Number	27
Alternate Webpage(s)	http://zums.ac.ir/journal/article-1-5224-fa.pdf
Alternate Webpage(s)	https://doi.org/10.30699/jambs.27.122.1
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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