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Early weaning programs rats to have a dietary preference for fat and palatable foods in adulthood
| Content Provider | Semantic Scholar |
|---|---|
| Author | Oliveira, Lisiane Dos Santos Lima, Deise Pereira De Silva, Amanda Alves Da Silva, Matilde Cesiana Da Manhães-De-Castro, Raul |
| Copyright Year | 2011 |
| Abstract | The objective of this work was to study the effect of early weaning on alimentary preference for the macronutrients protein, carbohydrate and fat in adult rats. Male Wistar rat pups were weaned by separation from the mother at 15 (D15) or 30 (D30) days old. Body weight and food intake were measured every 30 days until pups were 150 days old. At 110 days of age, the alimentary preference was evaluated for 1h on 3 consecutive days. At 120 days of age, the palatable diet test was conducted during 3 consecutive 24-h periods. Body weight and food intake were not altered, but early weaning in rats induced an alimentary preference to fat and hyperphagia of a palatable diet. In conclusion, early weaning, although did not modify body weight or basal food intake, promoted an increased preference for palatable and fatty foods. This demonstrates that early weaning is not capable of promoting perceptible alterations of alimentary behavior under normal laboratory conditions. However, in the presence of a stimulating factor such as a choice of nutrients or a palatable diet, a possible latent effect on dietary preferences may become apparent. Over the long term, this preference for foods with high caloric density can lead to obesity and metabolic perturbations. |
| Starting Page | 75 |
| Ending Page | 80 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.beproc.2010.09.005 |
| PubMed reference number | 20934490 |
| Journal | Medline |
| Volume Number | 86 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/S0376635710002457 |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/S0376635710002457?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/j.beproc.2010.09.005 |
| Journal | Behavioural Processes |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
