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Production of Poly(lactic acid)/Organoclay Nanocomposite Scaffolds by Microcompounding and Polymer/Particle Leaching
| Content Provider | Semantic Scholar |
|---|---|
| Author | Ozkoc, Guralp Kemaloglu, Sebnem Quaedflieg, Martin |
| Copyright Year | 2009 |
| Abstract | Organoclay reinforced poly(lactic acid) (PLA)/poly(vinyl alcohol) (PVA) blend based porous nanocomposite scaffolds are prepared by microcompounding/injection molding and subsequent polymer (PVA)/particle (NaCl) leaching method. The objective of the study is to investigate the effect of clay content on the properties of scaffolds for tissue engineering. It is revealed from X-ray diffraction and TEM studies that incorporation of PVA to PLA matrix as a polymeric porogen enhance the state of dispersion of clay particles resulting in an exfoliated structure. The porosities of all the scaffolds are higher than 70% and the pores are well-interconnected as observed by SEM. The addition of clay to the scaffolds improves the compressive modulus. Differential scanning calorimeter analysis shows that Tg of neat-PLA is shifted to lower values when it is compounded with PVA. As a result, it is demonstrated that the method applied in this work can be a good candidate for production of polymeric scaffolds for tissue engineering applications. POLYM. COMPOS., 31:674–683, 2010. a 2009 Society of Plastics Engineers |
| Starting Page | 674 |
| Ending Page | 683 |
| Page Count | 10 |
| File Format | PDF HTM / HTML |
| DOI | 10.1002/pc.20846 |
| Alternate Webpage(s) | http://akademikpersonel.kocaeli.edu.tr/sebnem.kemaloglu/sci/sebnem.kemaloglu30.12.2010_09.58.14sci.pdf |
| Alternate Webpage(s) | https://doi.org/10.1002/pc.20846 |
| Volume Number | 31 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
