NDLI: Systemic inflammation as a risk factor for atherothrombosis.

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Systemic inflammation as a risk factor for atherothrombosis.

Content Provider	Semantic Scholar
Author	Leuven, Sander I. Van Franssen, R. M. E. Kastelein, John J. P. Levi, Marcel Stroes, Erik S. G. Tak, Paul Peter
Copyright Year	2008
Abstract	Several chronic inflammatory disorders, such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), and chronic infections that are associated with a chronic inflammatory state, such as human immunodeficiency virus (HIV) infection, are associated with an increased incidence of cardiovascular disease (CVD). Cardiovascular mortality is a major cause of death in patients with these disorders. Direct effects and indirect sequelae of systemic inflammation promote atherothrombotic vascular disease. Pathophysiological processes promoting atherogenesis can initiate years before the diagnosis of a chronic inflammatory disease is made, and since exposure to risk factors in this pre-clinical phase is widespread, early cardiovascular protection in these patients seems warranted.
Starting Page	3
Ending Page	7
Page Count	5
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/rheumatology/47/1/10.1093/rheumatology/kem202/2/kem202.pdf?Expires=1492595418&Key-Pair-Id=APKAIUCZBIA4LVPAVW3Q&Signature=Mbq0tNlYNzZHD4D2JKl8~IMze31yJ4yC2b8NV2yIO-oiPGjeooMz0bzdH6ldn9ZxWkoI~V9sKJSDthPpaaagJB7blC6qGiWFkTYvYvxCvn7p545QTZfasLrbL51vbefxu-JYNrTOIvBY4QjlOcdxFu8qdLRUI7spCE7irJdV0ZbdVF~n9DaOwQQv2yZRqMdWzxXa8JM2nplG5f-lsW4HCqFtlP0VG6Ke3dWpfoU9Ad9b~9kb~s-50Vc9FyCzZ8eNx9V8thTC~GPRysHUXek~~06TXjvqNxmC8hmQRj~oknHydc6h1hUFpIYhBzyuD8CSzMnunPvzHKbpOt3paXWDqw__
PubMed reference number	17702769v1
Volume Number	47
Issue Number	1
Journal	Rheumatology
Language	English
Access Restriction	Open
Subject Keyword	Cardiovascular Diseases Cessation of life Conflict (Psychology) HIV Infections Immunologic Deficiency Syndromes Inflammation Life Expectancy Lupus Erythematosus, Systemic Morbidity - disease rate Patients Peripheral Vascular Diseases Promotion (action) Rheumatoid Arthritis Sequela of disorder chronic infection chronic inflammatory disease
Content Type	Text
Resource Type	Article

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