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Rat pinealectomy: a modified direct visual approach.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Maganhin, Carla Cristina Simões, Ricardo Santos Fuchs, Luiz Fernando Portugal Oliveira-Filho, Ricardo Martins De Simões, Manuel De Jesus Neto, Joaquim Evêncio Baracat, Edmund Chada Soares, José M. |
| Copyright Year | 2009 |
| Abstract | PURPOSE To report a new, direct visual approach for rat pinealectomy. METHODS Eighty adult female rats (Rattus norvegicus albinus EPM-1 strain) were weighted and anesthetized intraperitoneally with 15 mg/kg xylazine and 30 mg/kg ketamine. The animal was fastened to a dissection table, an incision was made in the skin and the subcutaneous tissue, bringing the lambda into view. The skullcap was opened with a dental drill, bringing the cerebral hemispheres and the superior sagittal sinus into view. The pineal gland, located under the venous sinus, was removed in a single piece using tweezers. Next, the bone fragment was returned to its place and the surgical layers were sutured. RESULTS This new technique is easy to be done, avoids bleedings and removes only the pineal gland without damage to the remaining encephalon. In addition it makes possible the achievement of a sham surgery, allowing the pineal gland to remain intact. CONCLUSION The proposed technique intends to facilitate studies aiming to better understanding the complexity and importance of the pineal gland on reproductive and other body systems. |
| Starting Page | 29 |
| Ending Page | 43 |
| Page Count | 15 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.scielo.br/pdf/acb/v24n4/13.pdf |
| PubMed reference number | 19705033v1 |
| Volume Number | 24 |
| Issue Number | 4 |
| Journal | Acta cirurgica brasileira |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Brain Cerebral hemisphere structure (body structure) Cortical Cell Layer of the Cerebral Cortex Dental Drilling Excision of pineal gland Ketamine Nasal sinus Reproduction Sagittal plane Structure of venous sinus Subcutaneous Tissue Superior sagittal sinus Surgical incisions Suture Device Component Xylazine anatomical layer body system mg/kg |
| Content Type | Text |
| Resource Type | Article |
