NDLI: TNM stage II大腸癌の検索リンパ節数が予後に与える影響

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TNM stage II大腸癌の検索リンパ節数が予後に与える影響

Content Provider	Semantic Scholar
Author	角田, 明良健太郎, 中尾神山, 剛一平塚, 研之成田, 和広山崎, 勝雄渡辺, 誠司鈴木, 直人保田, 尚邦草野, 満夫
Copyright Year	2006
Abstract	目的: リンパ節転移陰性の大腸癌患者の予後は概ね良好であるが, その成績内容には大きな較差がある. 今回TNM stage II (stage II)症例を対象として, 検索リンパ節数の遠隔成績に与える影響を検討した. 方法: 1981年から2000年までに経験した大腸癌症例のデータベースよりstage II・III症例を抽出した. 生存率の比較はKaplan-Meier法とLog-rank testを用い, 多変量解析はCox regression modelを適用した. 結果: stage II229例とstage III204例が解析の対象となった. stage II症例の検索リンパ節数は, 年齢(P=0.0035), 緊急手術の有無(P=0.0010), および癌占居部位(P=0.0030)に影響を受けた. 同様にstage III症例では, 性(P=0.0108), 深達度(P=0.0080)に影響を受けた. stage II症例では検索リンパ節数の減少によりHazard比が増大したが, stage III症例では増大しなかった. 考察: stage II症例の遠隔成績は検索リンパ節数に依存した. 検索リンパ節数の少ないstage II症例は, 補助化学療法の適応になる可能性がある.
Starting Page	536
Ending Page	543
Page Count	8
File Format	PDF HTM / HTML
DOI	10.5833/jjgs.39.536
Volume Number	39
Alternate Webpage(s)	https://www.jstage.jst.go.jp/article/jjgs1969/39/5/39_5_536/_pdf
Alternate Webpage(s)	https://doi.org/10.5833/jjgs.39.536
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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