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Niveles séricos de leptina y su relación con la excreción de sodio en niños y adolescentes obesos
| Content Provider | Semantic Scholar |
|---|---|
| Author | Jensen, Alicia Noemí Maskin De López, Miryan Susana Mir, Claudia Nora Martínez, Margalef Pianesi, María Esther Ibañez De Erhard, Martin |
| Copyright Year | 2011 |
| Abstract | La obesidad se asocia con niveles elevados de leptina y la mayoria de los individuos obesos presentan resistencia "selectiva" a su accion metabolica sin disminucion del apetito ni aumento en el gasto energetico, con preservacion y estimulacion de la activacion del sistema simpatico a nivel central y de las acciones perifericas cardiovasculares y renales. Estos mecanismos podrian modificar la regulacion del metabolismo del sodio a nivel renal. Objetivo: identificar el comportamiento de los niveles sericos de leptina en asociacion a la excrecion urinaria de sodio en una poblacion de ninos y adolescentes obesos. Material y metodos: se estudiaron 190 ninos y adolescentes entre 5 y 15 anos: 125 con indice de masa corporal (IMC) percentilo = 95 constituyeron el grupo de obesos (OB) y 65 con IMC percentilo 5 - Obesity is associated with elevated levels of leptin and most obese individuals are "selectively" resistant to its metabolic action, without appetite loss or increased energy expenditure, with preservation and stimulation of the activation of the sympathetic system at both the central and peripheral cardiovascular and renal levels. These mechanisms could modify the regulation of sodium metabolism in the kidney. Objective: To determine whether there is any correlation among between serum leptin levels and urinary sodium excretion in a population of obese children and adolescents an obese, children and adolescents. Material and methods: 190 children and adolescents between 5 and 15 years of age were studied: 125 with body mass index (BMI) = 95 percentile constituted the obese group (OB) and 65 with BMI percentile 5 - |
| Starting Page | 127 |
| Ending Page | 135 |
| Page Count | 9 |
| File Format | PDF HTM / HTML |
| Volume Number | 48 |
| Alternate Webpage(s) | http://www.scielo.org.ar/pdf/raem/v48n3/v48n3a01.pdf |
| Alternate Webpage(s) | http://www.saem.org.ar/boletin/adjuntos/Maskin%20y%20col.%20RAEM%202011.pdf |
| Alternate Webpage(s) | http://www.raem.org.ar/numeros/2011-vol48/numero-03/ENDO3-Maskin-ing.pdf |
| Alternate Webpage(s) | http://www.raem.org.ar/numeros/2011-vol48/numero-03/ingles/ENDO3-Maskin-Traduccion.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
