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La Hormona de Crecimiento en el Sistema Nervioso Central
| Content Provider | Semantic Scholar |
|---|---|
| Author | Santiago, Citlalli Regalado Meraz, María Leonor López Aguilar, Enrique Juárez |
| Copyright Year | 2012 |
| Abstract | Growth hormone (GH) is a multifunctional molecule that stimulates body growth as well as influences the metabolism of lipids and proteins and the proliferation, differentiation and survival of different cell types. Even the mechanism by which GH exerts its actions is variable. This hormone can exert it directly through the activation of a specific receptor or by stimulating secondary effectors like the insulin-like growth factor type I (IGF-I). Traditionally, the pituitary gland has been considered as the main source of production of GH. However, it is now known that this hormone is produced locally in various tissues in which exert an autocrine action. Moreover, this hormone has been detected at the earliest stage of development even before the formation and activation of the pituitary gland suggesting a central role of the GH in the beginning of life. Recent studies have suggested a role of GH in the development and function of the central nervous system (CNS). Experimental data support a role of GH in the CNS ranging from regulation of neural stem cell biology to its participation in the maintenance of cognitive processes such as learning and memory. The present review compiles evidence that support a “cerebral” function of GH. |
| Starting Page | 29 |
| Ending Page | 35 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| Volume Number | 12 |
| Alternate Webpage(s) | http://www.medigraphic.com/pdfs/veracruzana/muv-2012/muvs121d.pdf |
| Alternate Webpage(s) | https://www.uv.mx/rm/num_anteriores/revmedica_vol_especial_2012/articulos/la_hormona.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
