Transformations of 2-trifluoroacetyl-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridines by the action of ethyl propynoate. A novel synthesis of 2-trifluoroacetyl-4,7,8,9-tetrahydro-1H-pyrrolo[2,3-d]azocines

Content Provider	Semantic Scholar
Author	Voskresenskii, L. G. Borisova, Tatiana N. Vorob’eva, T. A. Grishachkina, O. V. Kulikova, Larisa N. Chernyshev, A. I. Varlamov, Alexey V.
Copyright Year	2006
Abstract	Abstract2-Trifluoroacetyl-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridines reacted with ethyl propynoate in acetonitrile and methanol to give ethyl 2-trifluoroaceyl-4,7,8,9-tetrahydro-1H-pyrrolo[2,3-d]azocine-5-carboxylates. The reactions of 2-trifluoroacetyl-1-vinyl-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridines with ethyl propynoate in alcohols were accompanied by cleavage of the tetrahydropyridine fragment with formation of alkyl 3-{benzyl[2-(3-alkoxy-5-trifluoroacetyl-1-vinyl-1H-pyrrol-2-yl)ethyl]amino}acrylates.
Starting Page	1851
Ending Page	1855
Page Count	5
File Format	PDF HTM / HTML
DOI	10.1134/S1070428006120165
Volume Number	42
Alternate Webpage(s)	https://page-one.springer.com/pdf/preview/10.1134/S1070428006120165
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article