NDLI: An economic evaluation of hepatitis A vaccination in Dutch military personnel.

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An economic evaluation of hepatitis A vaccination in Dutch military personnel.

Content Provider	Semantic Scholar
Author	Buma, Hopperus Beutels, Philippe Damme, Piet Van Tormans, Guy Doorslaer, E. K. A. Van Leentvaar-Kuijpers, A.
Copyright Year	1998
Abstract	We analyzed the cost-effectiveness of hepatitis A vaccination regimens using a mathematical simulation model. Passive immunization and two active vaccination strategies (with and without prior screening) were compared with "doing nothing." Hepatitis A antibodies were determined in 2,325 Dutch marines; other input data were retrieved from published and unpublished sources. The prevalence of hepatitis A antibody was 14%. Screening before vaccination was identified as appropriate at a prevalence > 20%. Passive immunization was the cheapest prevention for a single 6-month deployment per 10 years. The inactivated vaccine containing 1,440 enzyme-linked immunosorbent assay units without prior screening was identified as the best option for more frequent deployments. It was cost-saving with two or more missions per 10 years. A 5.3% hepatitis A attack rate validated the investment for this policy. Overall, immunization with inactivated hepatitis A vaccine without prior screening proved to be the optimum strategy for troops at regular risk.
Starting Page	1423
Ending Page	1430
Page Count	8
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.crd.york.ac.uk/CRDWeb/PrintPDF.php?AccessionNumber=21998001278&Copyright=NHS+Economic+Evaluation+Database+(NHS+EED)%3Cbr+/%3EProduced+by+the+Centre+for+Reviews+and+Dissemination+%3Cbr+/%3ECopyright+%26copy%3B+2013+University+of+York%3Cbr+/%3E
PubMed reference number	9715622v1
Volume Number	163
Issue Number	8
Journal	Military medicine
Language	English
Access Restriction	Open
Subject Keyword	Deploy Enzyme-Linked Immunosorbent Assay Hepatitis A Vaccines Hepatitis B Surface Antigen Vaccine Mathematics Relative Biological Effectiveness Religious Missions Scientific Publication Vaccination passive immunization procedure
Content Type	Text
Resource Type	Article

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