NDLI: No expression of porcine endogenous retrovirus after pig to monkey xenotransplantation

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No expression of porcine endogenous retrovirus after pig to monkey xenotransplantation

Content Provider	Semantic Scholar
Author	Hwang, Seongsoo Jung, Yi-Deun Cho, Kahee Ock, Sun-A Oh, Keon-Bong Kim, Heui-Soo Ahn, Curie Park, Jin-Ki Im, Seoki
Copyright Year	2014
Abstract	This study was performed to investigate the expression of two porcine endogenous retrovirus (PERV) elements, PERV gag and full-length conserved PERV, in blood cells collected periodically from organ-recipient monkeys that underwent pig to non-human primate xenotransplantation. The heart and kidney-respectively acquired from α-1,3-galactosyltransferase knockout (GT-KO) pigs that survived for24 and 25 days-were xenografted into cynomolgus monkeys. The two PERV elements expressed in the xenografted GT-KO pig organs were not present in the blood cells of the recipient monkeys. In the present study, we deduced that PERVs are not transmitted during GT-KO pig to monkey xenotransplantation.
Starting Page	90
Ending Page	93
Page Count	4
File Format	PDF HTM / HTML
DOI	10.5625/lar.2014.30.2.90
PubMed reference number	24999364
Journal	Medline
Volume Number	30
Alternate Webpage(s)	https://synapse.koreamed.org/Synapse/Data/PDFData/0169LAR/lar-30-90.pdf
Alternate Webpage(s)	https://doi.org/10.5625/lar.2014.30.2.90
Journal	Laboratory animal research
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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