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Progressive depletion of mtDNA in mitochondrial myopathy.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Durham, Steve E. Brown, Denise T. Turnbull, Douglass Matthew Chinnery, Patrick F. |
| Copyright Year | 2006 |
| Abstract | The authors studied seven patients with mitochondrial DNA (mtDNA) myopathy. Over time, there was a progressive depletion of mtDNA, which preferentially affected wild-type mitochondrial genomes. This suggests that loss of wild-type mtDNA is a major feature of mtDNA myopathy, and preventing wild-type mtDNA depletion has treatment implications. |
| Starting Page | 1700 |
| Ending Page | 1701 |
| Page Count | 2 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.neurology.org/content/67/3/504.full.pdf |
| PubMed reference number | 16894115v1 |
| Volume Number | 67 |
| Issue Number | 3 |
| Journal | Neurology |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | DNA, Mitochondrial Genome Genome, Mitochondrial Mitochondrial Myopathies Myopathy Patients |
| Content Type | Text |
| Resource Type | Article |