NDLI: Myoinositol augments insulin release from perfused rat pancreas

Content Provider	Semantic Scholar
Author	Szkudelski, Tomasz Chichłowska, J. Kliber, Agnes
Copyright Year	1999
Abstract	To test the direct influence of myoinositol on insulin release, rat pancreases were perfused with a medium containing glucose (6.6 mmol/L) or glucose with myoinositol at concentrations of 0.15, 1.55 or 15.5 mmol/L. Myoinositol at the lowest concentration was without effect. At concentrations of 1.55 and 15.5 mmol/L inositol significantly augmented insulin secretion; the total amount of insulin released during perfusions (30 min) with this compound was 508 and 478 \|iU, respectively vs 353 J IU secreted during the same time of perfusion without inositol. It seems quite possible that inositol may augment insulin secretion by formation of ATP, inositol phospholipids or inositol hexaphosphate.
Starting Page	107
Ending Page	113
Page Count	7
File Format	PDF HTM / HTML
DOI	10.22358/jafs/68813/1999
Volume Number	8
Alternate Webpage(s)	http://www.jafs.com.pl/pdf-68813-7054?filename=Myoinositol+augments.pdf
Alternate Webpage(s)	https://doi.org/10.22358/jafs%2F68813%2F1999
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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