NDLI: Synthesis and photophysical evaluations of fluorescent quaternary bipyridyl-1,8-naphthalimide conjugates as nucleic acid targeting agents

Content Provider	Semantic Scholar
Author	Ryan, Gary J. Elmes, Robert B. P. Quinn, Susan J. Gunnlaugsson, Thorfinnur
Copyright Year	2012
Abstract	A family of organic molecules containing the DNA intercalating chromophores, 4-nitro- and 4-amino 1,8-naphthalimide, conjugated to a diquat derivative by an ‘orthogonal’ phenyl spacer have been prepared and characterised. Their binding interactions with double-stranded DNA were studied by a variety of spectroscopic techniques. These charged organic compounds are found to exhibit excellent binding affinities to DNA with binding constants comparable to those exhibited by metal complexes.
Starting Page	175
Ending Page	188
Page Count	14
File Format	PDF HTM / HTML
DOI	10.1080/10610278.2011.638381
Volume Number	24
Alternate Webpage(s)	https://researchrepository.ucd.ie/bitstream/10197/4324/1/2012_Ryan_Supramol.pdf
Alternate Webpage(s)	http://eprints.maynoothuniversity.ie/6992/1/RE-Synthesis.pdf
Alternate Webpage(s)	https://doi.org/10.1080/10610278.2011.638381
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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