NDLI: Mecanismos bioquímicos de la leptina implicados en el desarrollo de la obesidad

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Mecanismos bioquímicos de la leptina implicados en el desarrollo de la obesidad

Content Provider	Semantic Scholar
Author	Hernández, Mario Eduardo Acosta Morales, Fernando Rafael Ramos Henríquez, José Bernardo Héctor Escobar Muñoz, José J. Castillo, Pamela Escobar Rodríguez, Rosa Virginia García Planell, Claudia Belén Ortega Croda-Todd, María Teresa Pérez, Eloy Gasca
Copyright Year	2015
Abstract	Obesity is characterized by an excessive accumulation of body fat of a higher caloric intake to energy consumption. At the present time it is considered a public health problem worldwide. It is a complex and multifactorial disease, which is developed by different factors, such as genetics, diet, physical inactivity and social conditions. It is now known that the regulation of body weight and body composition depends on the balance between energy intake and energy consumed by the body; these mechanisms are regulated by a bidirectional signaling that occurs between the gastrointestinal (GI) and central nervous system (CNS) through mechanisms acting in the short term and long term, allowing a relatively stable body weight despite daily fluctuations in diet and energy expenditure. One of the proposals to explain the overweight and obesity is an energy imbalance mediated leptin signaling, because leptin controls body fat tissue and, hence, body weight. Some studies showed that exist a strong correlation between serum leptin levels and the percentage of body fat. Deficiency in the production and signaling of this hormone would be related to this pathology. This paper tries to explain the mechanisms of leptin and its relationship with obesity.
Starting Page	103
Ending Page	113
Page Count	11
File Format	PDF HTM / HTML
Volume Number	15
Alternate Webpage(s)	http://www.medigraphic.com/pdfs/veracruzana/muv-2015/muv152g.pdf
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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