NDLI: Role of Polymorphic Loci in HLA-Region rs2647012 and rs805288 in the Development of Non-Hodgkin’s Malignant Lymphomas in Western Siberia

Please wait, while we are loading the content...

Role of Polymorphic Loci in HLA-Region rs2647012 and rs805288 in the Development of Non-Hodgkin’s Malignant Lymphomas in Western Siberia

Content Provider	Semantic Scholar
Author	Weiner, Alexandra S. Berezina, Oksana V. Ovchinnikov, V. S. Surovtseva, M. N. Voropaeva, Elena N. Pospelova, Tatiana I. Filipenko, Maxim L.
Copyright Year	2014
Abstract	The data of genome-wide association analysis suggest that human 6p21.3 chromosomal region (localization of HLA genes) contains polymorphic loci infl uencing the risk of developing non-Hodgkin’s lymphomas. We analyzed association of rs2647012 and rs805288 loci with the risk for non-Hodgkin’s malignant lymphomas in the population of Western Siberia. Allele and genotype frequencies were determined in the group of 298 patients and in the control group including 551 individuals. Subgroups of diffuse large B-cell lymphoma (86 patients) and follicular lymphoma (25 patients) were analyzed separately. An association of rs2647012 А/А genotype with increased risk of the disease (OR = 2.78, p = 0.002) was detected in the subgroup of diffuse large B-cell lymphoma.
Starting Page	180
Ending Page	183
Page Count	4
File Format	PDF HTM / HTML
DOI	10.1007/s10517-014-2520-2
PubMed reference number	24958370
Journal	Medline
Volume Number	157
Alternate Webpage(s)	https://page-one.springer.com/pdf/preview/10.1007/s10517-014-2520-2
Alternate Webpage(s)	https://doi.org/10.1007/s10517-014-2520-2
Journal	Bulletin of Experimental Biology and Medicine
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in