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In vivo fiber-optic confocal reflectance microscope with an injection-molded plastic miniature objective lens.
Content Provider | Semantic Scholar |
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Author | Carlson, Kristen D. Chidley, Matthew D. Sung, Kung-Bin Descour, Michael Gillenwater, Ann Follen, Michele Richards-Kortum, Rebecca R. |
Copyright Year | 2005 |
Abstract | For in vivo optical diagnostic technologies to be distributed to the developed and developing worlds, optical imaging systems must be constructed of inexpensive components. We present a fiber-optic confocal reflectance microscope with a cost-effective injection-molded plastic miniature objective lens for in vivo imaging of human tissues in near real time. The measured lateral resolution is less than 2.2 microm, and the measured axial resolution is 10 microm. Confocal images of ex vivo cervical tissue biopsies and in vivo human lip taken at 15 frames/s demonstrate the microscope's capability of imaging cell morphology and tissue architecture. |
Starting Page | 1 |
Ending Page | 5 |
Page Count | 5 |
File Format | PDF HTM / HTML |
Alternate Webpage(s) | http://www.remicalm.com/publications/2005/vfo.pdf |
PubMed reference number | 15813514v1 |
Volume Number | 44 |
Issue Number | 10 |
Journal | Applied optics |
Language | English |
Access Restriction | Open |
Subject Keyword | A Fibers Biopsy Body tissue Cellular Morphology Dental caries Epithelium Eye Frame (physical object) Malignant Neoplasms Microscope Device Component Neck Optic Atrophy, Autosomal Dominant Oral cavity Tissue fiber |
Content Type | Text |
Resource Type | Article |