NDLI: uided natural product isolation via solid-supported chemodosimetric fl uorescent probe †

Content Provider	Semantic Scholar
Author	Jeon, Hongjun Lim, Chaemin Kim, Sanghee
Copyright Year	2015
Abstract	As a new model of chemical assay-guided natural product isolation, an effective chemodosimetric assay system was devised. Our chemical assay system features a fluorogenic chemodosimeter immobilized on a solid support, which offers advantages in identifying the desired compounds in complex natural product mixtures. To isolate only compounds with the target functional groups, the click chemistry concept was adopted. The model system presented here was developed for natural products with a terminal alkyne. Using our newly designed alkyne sensing beads with the aforementioned features, we have readily identified, quantified, and isolated compounds with a terminal alkyne group from plant extracts.
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://pubs.rsc.org/en/content/articlepdf/2015/sc/c5sc00360a
Alternate Webpage(s)	http://pubs.rsc.org/en/content/articlepdf/2015/sc/c5sc00360a
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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