NDLI: Dietary methionine source and level affect hepatic sulfur amino acid metabolism of broiler breeder hens

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Dietary methionine source and level affect hepatic sulfur amino acid metabolism of broiler breeder hens

Content Provider	Semantic Scholar
Author	Wan, Jianmei Ding, X. M. Wang, Jianping Bai, Shiping Peng, Huanwei Luo, Yuheng Su, Zhuowei Xuan, Yue Zhang, Keying
Copyright Year	2017
Abstract	A study was carried out to investigate the effects of dietary methionine source and level on plasma free amino acids patterns and the expression of genes involved in hepatic methionine metabolism in broiler breeders. A total of 2184 broiler breeders were assigned to 13 dietary treatments, with eight replicates per treatment. The 13 treatments included one control group and 12 additional treatments employing two sources and six levels (0.05, 0.10, 0.15, 0.20, 0.25 and 1.00%). Higher plasma methionine concentration was measured for DL-methionine (DLM) treated hens. Plasma alanine concentration was linearly increased as DLM or 2-hydroxy-4-(methylthio) butanoic acid (HMTBA) supplementation level increased. There was a linear increase in concentrations of tyrosine, valine, glycine and serine as dietary DLM supplementation level increased. Hens treated with DLM had higher relative expression of ADA than those fed HMTBA. The expression of MS, ADA, SAHH and MAT2A changed quadratically as HMTBA supplementation level increased, while the expression of GNMT and SAHH changed quadratically as DLM supplementation level increased. In conclusion, the effects of HMTBA on plasma free amino acid patterns and the expression of hepatic genes involved with methionine are different from DLM.
Starting Page	2016
Ending Page	2024
Page Count	9
File Format	PDF HTM / HTML
PubMed reference number	28776913
Alternate Webpage(s)	https://doi.org/10.1111/asj.12882
DOI	10.1111/asj.12882
Journal	Animal science journal = Nihon chikusan Gakkaiho
Volume Number	88
Language	English
Access Restriction	Open
Subject Keyword	ADENOSINE DEAMINASE AHCY gene Alanine Amino Acid Metabolism, Inborn Errors Amino Acids Animal for breeding Butyric Acid MAT2A gene PersonNameUse - assigned Tyrosine Valine amino acid metabolism glycine N-methyltransferase activity methionine metabolism sulfur amino acid metabolic process
Content Type	Text
Resource Type	Article

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