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Studies on an antimicrobial activity of metal (Mn, Fe, Co, Ni, and Cu) chelates of 1, 2 naphthoquinone 1-oxime
| Content Provider | Semantic Scholar |
|---|---|
| Author | Jadhav, V. B. Gonewar, N. R. Jadhav, K. D. Sarawadekar, R. G. |
| Copyright Year | 2014 |
| Abstract | Transition metal chelates of the type M (NQO) 2 where M = Mn, Fe, Co,Ni, Cu: NQO = 1, 2 napthoquinone 1-oxime have been synthesized. X-ray studies have been carried out for Mn and Cu chelate of 1, 2 napthoquinone 1-oxime and the chelate of manganese belongs to Triclinic, a = 6.3580, b = 18.9591 c = 7.5697 A 0 , α = 100.429, β = 74.757, γ = 66.998, and copper chelate belongs to triclinic, a = 7.5528, b = 5.8689 c = 13.6719 A 0 , α = 63.541, β = 92.028, γ = 103.795. Their particle sizes are in the range of 15-42 nm. All chelates have been characterized by modern methods such as elemental analysis, FTIR and Electronic spectra.Scanning electron microscopy of chelates was carried out. The ligand and the metal chelates have been screened for antimicrobial activity on gram positive, gram negative bacteria and fungi. The results are compared with cisplatin as standard chemotherapy agent.Mechanism of hydrolysis of metalchelates is discussed. |
| Starting Page | 13 |
| Ending Page | 19 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| DOI | 10.9790/3008-09111319 |
| Volume Number | 9 |
| Alternate Webpage(s) | http://iosrjournals.org/iosr-jpbs/papers/Vol9-issue1/Version-1/C09111319.pdf |
| Alternate Webpage(s) | https://doi.org/10.9790/3008-09111319 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
