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Nanostructured Thin Films for Fluorescence Enhancement
| Content Provider | Semantic Scholar |
|---|---|
| Author | Lévêque-Fort, Sandrine Fort, Emmanuel Moal, E. Le Lacharme, J.-P. Fontaine-Aupart, M.-P. Ricolleau, Christian |
| Copyright Year | 2004 |
| Abstract | Fluorescence is widely used as a spectroscopic tool or for biomedical imaging, in particular for DNA chips. Nanostructured metallic substrates permit to locally enhance the fluorescence signal which offer the possibility both to detect very small fluorophore concentrations and to trace precisely the biomarkers. We have developed substrates made of silver or gold nanoparticles covered with a spacer layer of alumina. Double metallic and dielectric gradients permit to directly map the fluorescence enhancement factor and to determine the best condition for maximum enhancement. One and two photons excitations are studied. Fluorescence enhancement reaches two orders of magnitudes. Lifetime measurements reveal additional information on the decay channels induced by the nanoparticle presence. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://nathan.instras.com/ResearchProposalDB/doc-103.pdf |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Aluminum Oxide Artificial nanoparticles Biological Markers British Informatics Olympiad Dyes Excitation Fluorescence Gradient Medical imaging Photons Silver Spacer Device Component orders - HL7PublishingDomain |
| Content Type | Text |
| Resource Type | Article |
