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Synthesis and Biological Evaluation of Pyrido(2,3-d)pyrimidine-carboxylate Derivatives.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Shanmugasundaram, Prasad Harikrishnan, N. Aanandini, M. Vijey Kumar, M. Sathish Sateesh, J. N. |
| Copyright Year | 2011 |
| Abstract | Ethyl-5-amino-8-(4-halophenyl)-2-methyl-4,7-dioxo-3,4,5,6,7,8-hexahydro pyrido(2,3-d) pyrimidine-6-carboxylate and ethyl-5-amino-8-(4-halophenyl)-2-amino-4,7 dioxo-3,4,5,6,7,8 hexahydropyrido(2,3-d)pyrimidine-6-carboxylate derivatives have been synthesized through nucleophilic substitution reactions with the use of amidines, followed by 4haloanilines and malonic acid. These synthesized novel derivatives have been confirmed by elemental analysis, IR, 1 H NMR and mass spectra. These novel derivatives have also been screened for antibacterial, antifungal and antitumor activity. |
| File Format | PDF HTM / HTML |
| DOI | 10.1002/chin.201131152 |
| Alternate Webpage(s) | http://nopr.niscair.res.in/bitstream/123456789/11178/1/IJCB%2050B(3)%20284-289.pdf |
| Alternate Webpage(s) | http://rasayanjournal.co.in/vol-2/issue-2/18.pdf |
| Alternate Webpage(s) | https://doi.org/10.1002/chin.201131152 |
| Volume Number | 42 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |