NDLI: Aspects Épidémiologiques, Cliniques et Évolutifs des Cas Compliqués de Fièvre de la Vallée du Rift au District Sanitaire de Tchintabaraden (Niger)

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Aspects Épidémiologiques, Cliniques et Évolutifs des Cas Compliqués de Fièvre de la Vallée du Rift au District Sanitaire de Tchintabaraden (Niger)

Content Provider	Semantic Scholar
Author	Doutchi, Mahamadou Maidagi, O. Mohamed, A. Ould Sibongwere, Deo Danbouzoua, N. Kinda, Moumouni Kojan, Richard Shepherd, Susan E. Ouattara, Ali
Copyright Year	2017
Abstract	RESUME Introduction. La fievre de la Vallee du Rift (FVR) est une zoonose virale, transmise par les arthropodes. Bien que la maladie soit generalement sans gravite chez l’homme, des formes compliquees sont possibles, de type hemorragique et neurologique. Objectif. Decrire les aspects epidemiologiques, cliniques et evolutifs des cas compliques de FVR a l’hopital de district de Tchintabaraden, au Niger. Materiels et methodes. Etude transversale sur des cas de FVR de la periode du 1er septembre au 31 decembre 2016. Les cas suspects de FVR etaient hospitalises au centre de traitement ouvert par l’ONG medicale ALIMA (The Alliance for International Medical Action) et son partenaire BEFEN (Bien-etre de la Femme et de l’Enfant au Niger) au sein de l’hopital de district, mais seuls les cas confirmes et recents ont ete retenus et analyses. Resultats. Sur les 38 cas confirmes de FVR, nous avons trouve 17 infections recentes, qui sont analysees dans la suite de ce travail. Le sex-ratio H/F etait de 1.8 et l'âge moyen de 23 ans avec des extremes de 3 et 70 ans. Les piqures de moustiques, le contact direct avec des animaux avortes ou morts, et la consommation frequente de lait de ces animaux etaient des facteurs de risque observes chez tous les patients. Des manifestations hemorragiques et neurologiques ont ete observees chez respectivement 14 patients (82.3%) et 5 patients (2.41%). Les analyses biologiques ont montre un taux moyen de transaminases (ASAT) de 535 UI/L associe a une thrombocytopenie avec une valeur moyenne de 47000 mm3. La letalite globale etait de 29.4% (n=5). Conclusion. Premiere epidemie de fievre de la vallee du rift rapportee au Niger, la maladie est associee a une forte letalite au stade des complications. Nos resultats justifient la mise en place d'une surveillance epidemiologique continue. ABSTRACT Introduction. Rift Valley fever (RVF) is a viral zoonosis transmitted by arthropods; The disease is generally benign in humans; however complications may be encountered. Objective. To describe epidemiological, clinical and prognostic aspects of complicated cases RVF at the Tchintabaraden District Hospital in Niger. Materials and methods. This was a cross-sectional study of the confirmed cases of RVF from 1 September to 31 December 2016. Suspected cases of RVF were hospitalized at the treatment center opened by the medical NGO ALIMA (The Alliance for International Medical Action) and its partner BEFEN (Bien-etre de la Femme et de l’Enfant au Niger) in the district hospital. Results. We found 17 recent infections among the 38 confirmed of RVF; only those cases of recent infections are presented. The sex ratio male/female was 1.8 and the average age was 23 years (range: 3 - 70 years). Mosquito bites, direct contact with aborted or dead animals and frequent milk intake of these animals were some of the risk factors that were present for all patients. Fourteen patients (82.3%° had hemorrhagic complications and five (29.41%) had neurological damage. Blood analysis showed elevated transaminases (ASAT) (mean 535 IU / L) associated with thrombocytopenia, (mean 47000 /mm3). Five patients died (lethality rate: 29.4%). Conclusion. The course of the first epidemic of Rift valley fever reported in Niger was characterized by a high lethality rate, mainly due to hemorrhagic and neurological complications. This finding emphasizes the need of continuous epidemiological surveillance.
File Format	PDF HTM / HTML
Volume Number	18
Alternate Webpage(s)	https://www.alima-ngo.org/uploads/eb2321d2045746102c30ca302b1159a5.pdf
Alternate Webpage(s)	http://www.hsd-fmsb.org/index.php/hsd/article/download/818/pdf_424
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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