NDLI: In vitro fertilization by intracytoplasmic sperm injection.

Please wait, while we are loading the content...

In vitro fertilization by intracytoplasmic sperm injection.

Content Provider	Semantic Scholar
Author	Tesarik, Jan Mendoza, Carmen Concepción Jimenez
Copyright Year	1999
Abstract	Intracytoplasmic sperm injection (ICSI) is the latest, and by far the most efficient, variant of micromanipulation-assisted fertilization, whereby a single spermatozoon is selected, aspirated into a microinjection needle and injected to the oocyte cytoplasm. The development of this technique is mainly linked to application in human assisted reproduction for which it enables fertilization with defective spermatozoa that would not otherwise be able to penetrate an oocyte by their proper means. Because ICSI by-passes many steps of the natural fertilization process, it offers an extremely interesting model for the study of basic mechanisms underlying fertilization. This is particularly true for oocyte activation, whose mechanism needs to be revisited in light of the current ICSI research. The massive application of ICSI in human infertility treatment also represents a huge laboratory in which the impact of different genetic and epigenetic anomalies of the male gamete on fertilization and embryonic development can be studied.
Starting Page	791
Ending Page	801
Page Count	11
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://hera.ugr.es/doi/14999080.pdf
Alternate Webpage(s)	http://users.isr.ist.utl.pt/~sm3/biomedica/fertilizacao/ICSI_BioEssays_1999.pdf
PubMed reference number	10462420v1
Volume Number	21
Issue Number	9
Journal	BioEssays : news and reviews in molecular, cellular and developmental biology
Language	English
Access Restriction	Open
Subject Keyword	Acrosome Aneuploidy Animal Model Animals, Laboratory Body Piercing Congenital Abnormality Embryonic Development Female infertility Fertilization Genomic Imprinting Germ Cells Imprinting (Psychology) Large Microinjections Micromanipulation Oocytes Oscillator Device Component Plasma membrane Sperm Injections, Intracytoplasmic Spermatozoa Cell Count sperm cell study of epigenetics
Content Type	Text
Resource Type	Article

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in