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Effects of Aqueous Extract of Purslane (portulaca Oleracea) on Hepatic Enzymes in Two Models of Renal Ischemia-reperfusion Injury in Rats (short Communication)
| Content Provider | Semantic Scholar |
|---|---|
| Author | Majid, Askaripour Reza, Fatemi Tabatabaei S. Forouzan, Hosseini Masome, Rashno Shahab, Ghaderi |
| Copyright Year | 2016 |
| Abstract | Objectives: This study investigated the effect of purslane on hepatic enzymes following renal ischemia-reperfusion (IR) injury in rats by two methods. Materials and Methods: In this experimental study, 36 male Wistar rats randomly divided into 6 groups (n = 6): I) previously nephrectomized control, II) simultaneously nephrectomized control, III) previously nephrectomized + IR, IV) simultaneously nephrectomized + IR, V) previously nephrectomized treated by aqueous extract of P. oleracea L. + IR, VI) simultaneously nephrectomized treated by aqueous extract of P. oleracea L. + IR control and ischemia-reperfusion groups received vehicle and treatment groups received aqueous extract of purslane (300 mg/kg). In model 1, the right kidney was nephrectomized, 20 days prior to experiment, in model 2; nephrectomy was done just before induction of 45 minutes ischemia and 24 hours reperfusion to the left kidney. Results: Hepatic enzymes were elevated after induction of ischemia reperfusion. Administration of purslane decreased hepatic enzymes. Conclusions: Purslane prevented liver damage more effectively in simultaneously nephrectomized model. |
| File Format | PDF HTM / HTML |
| Volume Number | 18 |
| Alternate Webpage(s) | https://www.sid.ir/FileServer/JE/88720160209.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
