NDLI: Inverse treatment planning for Gamma Knife radiosurgery.

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Inverse treatment planning for Gamma Knife radiosurgery.

Content Provider	Semantic Scholar
Author	Shepard, David M. Ferris, Michael C. Ove, Roger Ma, Lijun
Copyright Year	2000
Abstract	An inverse treatment planning system for Gamma Knife radiosurgery has been developed using nonlinear programming techniques. The system optimizes the shot sizes, locations, and weights for Gamma Knife treatments. In the patient's prescription, the user can specify both the maximum number of shots of radiation and a minimum isodose line that must surround the entire treatment volume. After satisfying all of the constraints included in the prescription, the system maximizes the conformity of the dose distribution. This automated approach to treatment planning has been applied retrospectively to a series of patient cases, and each optimized plan has been compared to the corresponding manual plan produced by an experienced user. The results demonstrate that this tool can often improve the tumor dose homogeneity while using fewer shots than were included in the original plan. Therefore, inverse treatment planning should improve both the quality and the efficiency of Gamma Knife treatments.
File Format	PDF HTM / HTML
DOI	10.1118/1.1328080
PubMed reference number	11190958
Journal	Medline
Volume Number	27
Issue Number	12
Alternate Webpage(s)	http://pages.cs.wisc.edu/~ferris/papers/MPH-inverse.pdf
Alternate Webpage(s)	http://pages.cs.wisc.edu/~ferris/papers/inverse.pdf
Journal	Medical physics
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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