NDLI: Quantification of Morphine, Codeine, and Thebaine in Home-Brewed Poppy Seed Tea by LC-MS/MS.

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Quantification of Morphine, Codeine, and Thebaine in Home-Brewed Poppy Seed Tea by LC-MS/MS.

Content Provider	Semantic Scholar
Author	Powers, Deborah Erickson, Stephen C. Swortwood, Madeleine J.
Copyright Year	2018
Abstract	Recently, medical examiners reported two cases of a 21-year-old male and 24-year-old male with high amounts of morphine in their blood at autopsy. It was suspected that the decedents ingested lethal amounts of morphine from home-brewed poppy seed tea. No studies to date have investigated opium alkaloid content extracted from poppy seeds by home-brewing methods. Various poppy seed products were purchased from online sources and extracted with four home-brewing methods representative of recipes found on drug user forums. Morphine, codeine, and thebaine were quantified in the tea extracts by liquid chromatography-tandem mass spectrometry using a validated analytical method. Morphine, codeine, and thebaine concentrations from seeds were <1-2788 mg/kg, <1-247.6 mg/kg, and <1-124 mg/kg, respectively. Alkaloid yield varied between extractions, but regardless of extraction conditions, lethal amounts of morphine can be rinsed from poppy seed coats by home-brewing methods.
Starting Page	1229
Ending Page	1235
Page Count	7
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://www.oregonpainguidance.org/wp-content/uploads/2018/02/Powers_et_al-2017-Journal_of_Forensic_Sciences.pdf?x91687=
PubMed reference number	28973785v1
Alternate Webpage(s)	https://doi.org/10.1111/1556-4029.13664
DOI	10.1111/1556-4029.13664
Journal	Journal of forensic sciences
Volume Number	63
Issue Number	4
Language	English
Access Restriction	Open
Subject Keyword	Alkaloids Codeine Drug abuser Extraction Ingestion Liquid Chromatography Morphine Opium Papaver Plant alkaloid Plant seeds Tandem Mass Spectrometry Tea Tree Oil Thebaine buying mg/kg
Content Type	Text
Resource Type	Article

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