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Preparative isolation and purification of sinomenine from Sinomenium acutum by centrifugal partition chromatography.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Cheong, Jong Hye Kim, Chul Young Kim, Jinwoong |
| Copyright Year | 2007 |
| Abstract | Preparative centrifugal partition chromatography (CPC) was successfully carried out for the separation of sinomenine from the methanolic extract of Sinomenium acutum stems and rhizomes. The optimum two-phase solvent system of CPC was composed of n-hexane/ethyl acetate/methanol/water at a volume ratio of 1:6:2:8 (v/v/v/v) with 0.1% triethylamine (TEA). Preparative CPC yielded 44.3 mg of sinomenine from 400 mg of MeOH extract with a purity of 96.9%. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.snupharm.ac.kr/jwkim/erp/erpmenus/professor_thesis/upLoadFiles/jss07-30.pdf |
| PubMed reference number | 17654620v1 |
| Volume Number | 30 |
| Issue Number | 13 |
| Journal | Journal of separation science |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Gas Chromatography-Mass Spectrometry Methanol Purity Rhizome Sinomenium Volume fraction ethyl acetate sinomenine triethylamine |
| Content Type | Text |
| Resource Type | Article |