Loading...
Please wait, while we are loading the content...
Similar Documents
Technical Note: Monte Carlo calculations of the AAPM TG‐43 brachytherapy dosimetry parameters for a new titanium‐encapsulated Yb‐169 source
| Content Provider | Semantic Scholar |
|---|---|
| Author | Reynoso, Francisco J. Iii, John J. Munro Cho, Sang Hyun |
| Copyright Year | 2017 |
| Abstract | Due to a number of distinct advantages resulting from the relatively low energy gamma ray spectrum of Yb-169, various designs of Yb-169 sources have been developed over the years for brachytherapy applications. Lately, Yb-169 has also been suggested as an effective and practical radioisotope option for a novel radiation treatment approach often known as gold nanoparticle-aided radiation therapy (GNRT). In a recently published study, the current investigators used the Monte Carlo N-Particle Version 5 (MCNP5) code to design a novel titanium-encapsulated Yb-169 source optimized for GNRT applications. In this study, the original MC source model was modified to accurately match the specifications of the manufactured Yb-169 source. The modified MC model was then used to obtain a complete set of the AAPM TG-43 parameters for the new titanium-encapsulated Yb-169 source. The MC-calculated dose rate constant for this titanium-encapsulated Yb-169 source was 1.19 ± 0.03 cGy·h-1·U-1, indicating no significant change from the values reported for stainless steel-encapsulated Yb-169 sources. The source anisotropy and radial dose function for the new source were also found similar to those reported for the stainless steel-encapsulated Yb-169 sources. The current results suggest that the use of titanium, instead of stainless steel, to encapsulate the Yb-169 core would not lead to any major change in the dosimetric characteristics of the Yb-169 source. The results also show that the titanium encapsulation of the Yb-169 source could be accomplished while meeting the design goals as described in the current investigators' published MC optimization study for GNRT applications. |
| Starting Page | 193 |
| Ending Page | 199 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| DOI | 10.1002/acm2.12111 |
| PubMed reference number | 28585277 |
| Journal | Medline |
| Volume Number | 18 |
| Alternate Webpage(s) | https://digitalcommons.wustl.edu/cgi/viewcontent.cgi?article=6956&context=open_access_pubs |
| Alternate Webpage(s) | http://digitalcommons.wustl.edu/cgi/viewcontent.cgi?article=6956&context=open_access_pubs |
| Journal | Journal of applied clinical medical physics |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
