NDLI: Vaccination against hepatitis B virus in Spain: a cost-effectiveness analysis.

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Vaccination against hepatitis B virus in Spain: a cost-effectiveness analysis.

Content Provider	Semantic Scholar
Author	Garuz, Roberto Arnal, José Miguel Forcén, Tarsicio Trinxet, Cristina Antón, Francisco Antoñanzas, F.
Copyright Year	1997
Abstract	A cost-effectiveness analysis was made to determine the effectiveness of the following strategies of mass immunization with the new recombinant vaccine against the hepatitis B virus in Spain: vaccination of adolescents, newborns, both populations, and vaccination plus passive immunization of newborns of HBsAg positive mothers. Decision trees supported on Markov models with Monte Carlo simulation have been used for the calculation of costs of the disease, and a mathematical model of differential equations was used for the simulation of the potential effectiveness of vaccination. The costs considered were those associated with the vaccination and travel of subjects, diagnosis, and treatment of the disease. The results are presented as additional cost or saving per case of infection prevented. In all assumptions, results showed that the most effective strategy for mass vaccination was the combination of vaccinating all adolescents together with active and passive immunization of children born to HBsAg positive mothers.
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.crd.york.ac.uk/crdweb/PrintPDF.php?AccessionNumber=21998006072&Copyright=NHS+Economic+Evaluation+Database+(NHS+EED)%3Cbr+/%3EProduced+by+the+Centre+for+Reviews+and+Dissemination+%3Cbr+/%3ECopyright+%26copy%3B+2017+University+of+York%3Cbr+/%3E
PubMed reference number	9364696v1
Volume Number	15
Issue Number	15
Journal	Vaccine
Language	English
Access Restriction	Open
Subject Keyword	Adolescent (age group) Cost Effectiveness Decision Support Techniques Financial cost Hepatitis B Surface Antigen Vaccine Hepatitis B Surface Antigens Hepatitis B Virus Herpesvirus 1, Cercopithecine Infant, Newborn Leucaena pulverulenta Mass Vaccination Mathematics Recombinants Trees (plant) passive immunization procedure
Content Type	Text
Resource Type	Article

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