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Comparison of fine needle aspiration cytology, radioisotopic and ultrasound scanning in the management of thyroid nodules.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Burke, Michael Martin Tellez, Marisol |
| Copyright Year | 1990 |
| Abstract | In 175 patients presenting with thyroid nodules, the diagnostic value in management of fine needle aspiration and cytology (FNAC), pertechnetate (99mTc) scanning and ultrasound imaging was examined. In 82 patients, the diagnosis was confirmed at operation; in the remaining 93, there was a follow-up period of at least 2 years. Thyroid cancer was found in 13 patients. For FNAC the sensitivity, specificity and positive predictive value for thyroid cancer were 92%, 85% and 41% respectively compared with 82%, 34% and 11% for 99mTc pertechnetate scanning, 75%, 61%, 19% for ultrasound and 73%, 58% and 19% for combined pertechnetate and ultrasound scanning. In 14% of patients, the aspirates were inadequate for cytology at the first examination. FNAC is therefore the preferable initial investigation and usually gives results adequate for a decision on surgical or medical management. With medical management and follow-up, ultrasound is of value in defining the nodule and the appearance of the rest of the gland. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://pmj.bmj.com/content/postgradmedj/66/781/914.full.pdf |
| PubMed reference number | 2176287v1 |
| Volume Number | 66 |
| Issue Number | 781 |
| Journal | Postgraduate medical journal |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Aspirate substance Fine needle aspiration biopsy Follow-Up Report Papillary thyroid carcinoma Patients Positive Predictive Value of Diagnostic Test Sodium Pertechnetate Tc 99m Thyroid Nodule Ultrasonography |
| Content Type | Text |
| Resource Type | Article |
