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Regeneration of fungiform taste buds: temporal and spatial characteristics.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Cheal, M. Oakley, Bruce |
| Copyright Year | 1977 |
| Abstract | The gross morphology of the tongue of the Mongolian gerbil Meriones unguiculatus), the location of papillae and taste buds, and the normal innervation pattern of the tongue and taste buds were determined. The chorda tympani nerve was interrupted to produce degeneration of fungiform taste buds. Regenerating chorda tympani axons followed the original nerve pathways in the tongue en route to the fungiform papillae in the epithelium where they initiated the regeneration of taste buds. The spatial distribution of reinnervated fungiform papillae and reformed taste buds was examined 7 to 19 days following surgery. Beginning at eight days following chorda tympani interruption there was a progressive increase, first, in the proportion of fungiform papillae that were reinnervated, and later in the number of reformed taste buds. On the basis of these measures it was concluded that a taste bud is reformed one to two days after reinnervation of its papilla. From the time course of reinnervation of the fungiform papillae it was calculated that some fibers regenerated at rates in excess of 2 mm/day. Regeneration was precise and systematic. The regenerating chorda tympani fibers accurately returned to the fungiform papillae; they did not follow the pathways of lingual nerve axons. In the initial stages of recovery both reinnervated papillae and reformed taste buds were preferentially located toward the front of the tongue; the reinnervation of posterior fungiform papillae was delayed. |
| Starting Page | 160 |
| Ending Page | 163 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://deepblue.lib.umich.edu/bitstream/handle/2027.42/49997/901720405_ftp.pdf?isAllowed=y&sequence=1 |
| Alternate Webpage(s) | https://deepblue.lib.umich.edu/bitstream/handle/2027.42/49997/901720405_ftp.pdf;sequence=1 |
| Alternate Webpage(s) | https://deepblue.lib.umich.edu/bitstream/handle/2027.42/49997/901720405_ftp.pdf?sequence=1 |
| PubMed reference number | 838892v1 |
| Volume Number | 172 |
| Issue Number | 4 |
| Journal | The Journal of comparative neurology |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Abducens Nerve Diseases Axon Bud - CHV concept Gerbil hair Ab.IgE:ACnc:Pt:Ser:Qn Gerbils Mongolian Spot Mongolian gerbil skin allergenic extract 20000 UNT/ML Injectable Solution Natural regeneration Papilla of tongue Structure of chorda tympani Structure of fungiform papillae of tongue Structure of lingual nerve Taste Buds Tissue fiber nerve supply |
| Content Type | Text |
| Resource Type | Article |
