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Comparison of Anti-Mullerian Hormone (AMH), Basal Follicle Stimulating Hormone (FSH), Estradiol and Antral Follicles Count as Predictors of Ovarian Response in in vitro Fertilization Program
| Content Provider | Semantic Scholar |
|---|---|
| Author | Samsulhadi Primariawan, Relly Yanuari Widhiarta, Kadek Dharma |
| Copyright Year | 2013 |
| Abstract | Ovarian stimulation response is crucial to be identified in in vitro fertilization program. There are several markers to identify suchresponse, including AMH, basal FSH, estradiol and AFC. This study aimed to find the difference AMH, basal FSH, estradiol andAFC as ovarian responsepredictors. This was an observational analytic study in infertile patients. Subjects performed bloodsampling 3-day menstrual cycle for inspection of AMH, basal FSH, E2 basal and antral follicle number calculation (AFC). Based onoocytes the number, the subjects were divided into groups of poor responders (� 4 oocytes) and good responders (oocytes 5-15). Weperformed correlation and regression test between AMH, basal FSH, AFC, and basal E2 with three indicators of ovarian stimulationresponse (number of oocytes at OPU, the number of preovulatory follicles and E2 levels at hCG administration).The results showeda significant difference in AMH levels (p = 0.001), basal FSH (p = 0.045), and AFC (p = 0.001) between poor and good responders.AMH correlated strongly and significantly with OPU (r = 0843, p = 0.001), number of preovulatory follicles (r = 0577, p = 0.001),and current E2 administration HCG (r = 0701 and p = 0.001). AFC also show a strong and significant correlation with the OPU (r= 0721, p = 0.001), number of preovulatory follicles (r = 0555, p = 0.002), and current E2 administration HCG (r = 0435, p =0021). Only basal FSH obtained by OPU had significant correlation (r = -0420, p = 0026). Basal E2 showed no significantcorrelations on all three indicators of ovarian response. In conclusion, AMH is a better predictor of ovarian response than AFC,basal FSH and basalE2.(MOG 2013;21 84-88) |
| File Format | PDF HTM / HTML |
| Volume Number | 21 |
| Alternate Webpage(s) | http://journal.unair.ac.id/download-fullpapers-mog2e3f042a0afull.pdf |
| Alternate Webpage(s) | http://journal.unair.ac.id/download-fullabstrak-8230-mog6d0563e060abs.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |