NDLI: In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of Brazilian strains of Burkholderia pseudomallei.

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In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of Brazilian strains of Burkholderia pseudomallei.

Content Provider	Semantic Scholar
Author	Bandeira, Tereza De Jesus Pinheiro Gomes Moreira, Camila Alencar Brilhante, Raimunda Sâmia Nogueira Castelo-Branco, Débora De Souza Collares Maia Neto, Manoel Paiva De Araújo Cordeiro, Rossana De Aguiar Rodrigues, Terezinha De Jesus Santos Rocha, Marcos Fébio Gadelha Sidrim, José Júlio Costa
Copyright Year	2013
Abstract	This study aimed at investigating the in vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against Burkholderia pseudomallei in planktonic and biofilm forms, through broth microdilution and resazurin-based viability staining, respectively. In planktonic growth, the strains were susceptible to the drugs, while in biofilm growth, significantly higher antimicrobial concentrations were required, especially for ceftazidime and imipenem, surpassing the resistance breakpoints. These results highlight the importance of the routine evaluation of biofilm antimicrobial susceptibility.
Starting Page	971
Ending Page	980
Page Count	10
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.repositorio.ufc.br/bitstream/riufc/8552/1/2013_art_dcbscmaia.pdf
PubMed reference number	24002089v1
Alternate Webpage(s)	https://doi.org/10.1128/AAC.00721-13
DOI	10.1128/AAC.00721-13
Journal	Antimicrobial agents and chemotherapy
Volume Number	57
Issue Number	11
Language	English
Access Restriction	Open
Subject Keyword	Amoxicillin / Clavulanate Burkholderia pseudomallei Ceftazidime Doxycycline Imipenem Microbial Biofilms Staining method Sulfamethoxazole Trimethoprim-Sulfamethoxazole Combination
Content Type	Text
Resource Type	Article

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