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Visualizing ncRNA Structural Evolution with Arc Diagrams
| Content Provider | Semantic Scholar |
|---|---|
| Author | Tsiros, Alyssa Harrison, Lane |
| Copyright Year | 2015 |
| Abstract | The second challenge of this year’s BioVis Symposium Design Contest was to create a visualization of noncoding RNA (ncRNA) structural evolution of the human accelerated region 1 (HAR1) gene in ancestral, denisovan, and human sequences. The commonly used chart types for this data, dot plots and node-link style graphs, do not support direct comparison of base pairings among the three structures. We propose a redesign that uses arc diagram visualization techniques to highlight conserved or otherwise evolved base pairings. These diagrams support the placement of unique and prevalent base pairings along a common scale and allow mapping task-specific features to color, providing viewers with a more direct means to identify differences in the structure predictions. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.biovis.net/sites/default/files/1_Alyssa_Tsiros_0.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
