Loading...
Please wait, while we are loading the content...
Similar Documents
Sentinel node dissection as definitive treatment for node negative breast cancer patients.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Ponzone, Riccardo Biglia, Nicoletta Maggiorotto, Furio Kubatzki, Franziska Elia, O. Rosa, Giovanni De Sismondi, Piero |
| Copyright Year | 2003 |
| Abstract | AIMS Negative sentinel node may predict tumour-free axillary nodes in breast cancer. We report the performance of sentinel node dissection at our Institution. METHODS We analysed data from 212 consecutive women with primary invasive breast tumours less than 3 cm in diameter and no axillary lymphadenopathy who underwent radioguided sentinel node dissection by means of 99mTc-colloidal albumin between 1999 and 2002. Completion axillary node dissection was performed if sentinel nodes contained metastases or if no sentinel nodes were identified. RESULTS Sentinel nodes were identified in 207/212 of the patients. Fifty-seven patients had tumour-positive sentinel nodes. Only tumour diameter showed significant association with sentinel node status (p<0.000). Per-operative histologic evaluation had a sensitivity of 67.3% and a negative predictive value of 90.4%. No subset of sentinel node positive patients was identified for whom axillary node dissection could be safely avoided. No recurrences were detected at a median follow-up of 15 months. CONCLUSION Radioguided sentinel node dissection offers a reliable way to assess nodal status in most breast cancer patients. In our experience, both preoperative lymphoscintigraphy and intraoperative histologic evaluation add useful information to the procedure. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://s3.amazonaws.com/publicationslist.org/data/piero.sismondi/ref-48/Sentinel%20node%20dissection%20as%20definitive%20treatment.pdf |
| PubMed reference number | 14602486v1 |
| Volume Number | 29 |
| Issue Number | 9 |
| Journal | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Anatomic Node Axillary lymphadenopathy Contain (action) Diameter (qualifier value) Mammary Neoplasms Negative Predictive Value of Diagnostic Test Para-aortic node Patients Radioisotope scan of lymphatic system Recurrence (disease attribute) Sentinel Lymph Node Sentinel node (disorder) Sinoatrial Node axillary lymph node dissection technetium Tc 99m human serum albumin colloid |
| Content Type | Text |
| Resource Type | Article |
