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Unstimulated salivary p53 in patients with oral lichen planus and squamous cell carcinoma.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Agha-Hosseini, Farzaneh Mirzaii-Dizgah, Iraj Miri-Zarandi, Najmeh Sadaat |
| Copyright Year | 2015 |
| Abstract | Unstimulated whole salivary p53 was evaluated in non-involved subjects, in patients suffering from oral lichen planus (OLP) and squamous cell carcinoma (SCC). A total of 34 patients with OLP, 24 patients suffering from oral SCC and 41 non-involved participants were enrolled. The unstimulated whole saliva p53 level was assayed by ELISA. Data was analyzed by ANOVA followed by the Tukey post hoc test. Saliva p53 concentration in patients with SCC (5.36±1.08) was significantly higher than in healthy participants (0.41±0.04) and in patients suffering from OLP (0.94±0.31). This study could not confirm the precancerous nature of OLP based on the relatively low p53 expressions in comparison to SCC. |
| File Format | PDF HTM / HTML |
| PubMed reference number | 26520632 |
| Journal | Medline |
| Volume Number | 53 |
| Issue Number | 7 |
| Alternate Webpage(s) | http://acta.tums.ac.ir/index.php/acta/article/download/4284/4239 |
| Alternate Webpage(s) | https://www.sid.ir/FileServer/JE/86520150709.pdf |
| Journal | Acta medica Iranica |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |