Hyperreflexia in axonal Guillain–Barré syndrome subsequent to Campylobacter jejuni enteritis

Content Provider	Semantic Scholar
Author	Kuwabara, Satoshi Nakata, Miho Sung, Jia-Ying Mori, Masahiro Yuki, Nobuhiro
Copyright Year	2002
Abstract	We describe a patient with the acute motor axonal neuropathy (AMAN) form of Guillain-Barré syndrome (GBS), who showed generalized hyperreflexia. A 24-year-old man developed acute paralysis following Campylobacter jejuni enteritis. He showed exaggerated tendon reflexes with abnormal reflex spread to other segments, and was initially diagnosed as having post-infectious myelitis. Nerve conduction studies showed motor axonal degeneration (the AMAN pattern), and increased soleus H-reflex amplitudes. His serum was positive for IgG antibodies to gangliosides GM1b and GalNAc-GD1a. He was treated with plasmapheresis, resulting in rapid recovery. Hyperreflexia was still present 12 months after onset when muscle strength was completely normal. This case provides further evidence that patients with AMAN can develop increased motor neuron excitability, and possible mechanisms for the hyperreflexia are discussed.
Starting Page	89
Ending Page	92
Page Count	4
File Format	PDF HTM / HTML
DOI	10.1016/S0022-510X(02)00088-6
PubMed reference number	12084449
Journal	Medline
Volume Number	199
Alternate Webpage(s)	https://api.elsevier.com/content/article/pii/S0022510X02000886
Alternate Webpage(s)	https://www.sciencedirect.com/science/article/pii/S0022510X02000886?dgcid=api_sd_search-api-endpoint
Alternate Webpage(s)	https://doi.org/10.1016/S0022-510X%2802%2900088-6
Journal	Journal of the Neurological Sciences
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article