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Myelofibrosis with myeloid metaplasia.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Tefferi, Ayalew |
| Copyright Year | 2000 |
| Abstract | Introduction Myelofibrosis with myeloid metaplasia (MMM) represents both agnogenic myeloid metaplasia (AMM) and the fibrotic stages of polycythemia vera (PV) and essential thrombocythemia (ET). The latter two conditions are also referred to as post polycythemic myelofibrosis (PPM) and post thrombocythemic myelofibrosis (PTM). MMM is currently classified under the broad category of chronic myeloid disorders (CMD). Classification of the CMDs is based on certain molecular, cytogenetic, morphologic, and clinical characteristics. In the context of a CMD, the demonstration of the bcr/abl genetic translocation between chromosomes 9 and 22 mandates a diagnosis of chronic myelocytic leukemia (CML). The bcr/abl–negative group may be divided into two major subgroups; the myelodysplastic syndromes (MDS) and the chronic myeloproliferative disorders (CMPD). MMM is classified under the latter group along with PV and ET. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://ishapd.org/1999/26.pdf |
| Alternate Webpage(s) | https://pdfs.semanticscholar.org/8a18/5ef118559d86a8247e0093978213a8b466cb.pdf |
| PubMed reference number | 10781623v1 |
| Volume Number | 342 |
| Issue Number | 17 |
| Journal | The New England journal of medicine |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | B-Cell Receptor Complex Chromosomal translocation Chromosomes Chronic Lymphocytic Leukemia Chronic myeloproliferative disorder Classification MYELODYSPLASTIC SYNDROME Myelodysplastic-Myeloproliferative Diseases Myeloid Leukemia Myeloid Leukemia, Chronic Myeloid Metaplasia Polycythemia Vera Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase Primary Myelofibrosis Thrombocythemia, Essential Thrombocytosis part per million (ppm) |
| Content Type | Text |
| Resource Type | Article |
