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An active DNA-based nanoprobe for photoacoustic pH imaging† †Electronic supplementary information (ESI) available: DNA sequences, optical characterisation and calculation details, Fig. S1–S8 and Tables S1, S2. See DOI: 10.1039/c8cc04007a
| Content Provider | Semantic Scholar |
|---|---|
| Author | Baumann, Kevin N. Fux, Alexandra C. Joseph, James Bohndiek, Sarah Elizabeth Hernández-Ainsa, Silvia |
| Copyright Year | 2018 |
| Abstract | We report an active DNA construct capable of probing pH through a photoacoustic (PA) ratiometric analysis approach. Our nanoprobe enables different PA readout in tissue mimicking phantoms in the range between pH 6.8 to 7.8 at physiologically relevant sodium concentrations. Thus, it represents a promising platform to probe pH values relevant to the tumor microenvironment using PA. |
| Starting Page | 10176 |
| Ending Page | 10178 |
| Page Count | 3 |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/c8cc04007a |
| PubMed reference number | 30137064 |
| Journal | Medline |
| Volume Number | 54 |
| Alternate Webpage(s) | https://pubs.rsc.org/en/content/articlepdf/2018/cc/c8cc04007a |
| Alternate Webpage(s) | https://doi.org/10.1039/c8cc04007a |
| Journal | Chemical communications |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |