Immunohistochemical localization of γ-aminobutyric acid- and aspartate-containing neurons in the rat deep cerebellar nuclei

Content Provider	Semantic Scholar
Author	Kumoi, Kazuo Saito, Naoaki Kuno, Takayoshi Tanaka, Chikako
Copyright Year	1988
Abstract	The immunohistochemical localization of gamma-aminobutyric acid (GABA)- and aspartate-containing neurons was evidenced in the rat deep cerebellar nuclei, using purified antisera to GABA and aspartate, respectively. Most GABA-containing neurons had small cell bodies and were scattered unevenly throughout the deep cerebellar nuclei. The medial cerebellar nucleus had a few GABA-containing cell bodies and interpositus and lateral nuclei contained many GABA-containing cell bodies. GABA-containing terminals were distributed throughout the nuclei. A large number of various-sized aspartate-containing cells were present in the deep cerebellar nuclei and most of these cells were large or medium-size. Aspartate-containing cells in the medial, interpositus and lateral nucleus were surrounded by GABA-like immunoreactive terminals, thereby suggesting the modulation of aspartate-containing neurons by GABA-ergic fibers from Purkinje cells.
Starting Page	302
Ending Page	310
Page Count	9
File Format	PDF HTM / HTML
DOI	10.1016/0006-8993(88)91487-4
PubMed reference number	3282599
Journal	Medline
Volume Number	439
Alternate Webpage(s)	https://api.elsevier.com/content/article/pii/0006899388914874
Alternate Webpage(s)	https://www.sciencedirect.com/science/article/pii/0006899388914874?dgcid=api_sd_search-api-endpoint
Alternate Webpage(s)	https://doi.org/10.1016/0006-8993%2888%2991487-4
Journal	Brain Research
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article