Molecular mechanisms of PKC[delta] in neurotoxin-induced apoptotic death of nigral dopaminergic neurons: relevance to the pathogenesis of Parkinson's disease

Content Provider	Semantic Scholar
Author	Yang, Yongjie
Copyright Year	2005
Abstract	v CHAPTER I: GENERAL INTRODUCTION 1 Dissertation Organization 1 Research Objective 2 Background and Literature Review 3 CHAPTER II: SUPPRESSION OF CASPASE-3 DEPENDENT PROTEOLYTIC ACTIVATION OF PROTEIN KINASE C5 BY SMALL INTERFERING RNA (SIRNA) PREVENTS MPP+-INDUCED DOPAMINERGIC DEGENERATION 57 Abstract 57 Introduction 58 Results 60 Discussion 68 Materials and Methods 73 Acknowledgements 83 References 102 CHAPTER III: PROTEOLYTICALLY ACTIVATED PKCÔ TRANSLOCATES TO THE NUCLEUS AND MEDIATES SER14 PHOSPHORYLATION OF HISTONE H2B IN NEUROTOXIN-INDUCED APOPTOTIC DEATH OF DOPAMINERGIC NEURONAL CELLS 112 Abstract 112 Introduction 113 Materials and Methods 117 Results 126 Discussion 138 References 164
File Format	PDF HTM / HTML
DOI	10.31274/rtd-180813-3335
Alternate Webpage(s)	https://lib.dr.iastate.edu/cgi/viewcontent.cgi?article=2608&context=rtd
Alternate Webpage(s)	http://lib.dr.iastate.edu/cgi/viewcontent.cgi?article=2608&context=rtd
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article