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Synthesis of 2,6-Bis(1H-indole-6-yl)-4H-pyran-4-ones via Leimgruber—Batcho Indole Synthesis.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Shahrisa, Aziz Ghasemi, Zarrin Saraei, Mahnaz |
| Copyright Year | 2009 |
| Abstract | 2,6-Bis(1H-indole-6-yl)-4H-pyran-4-one 4 was synthesized via Leimgruber–Batcho methodology starting from 2,6-bis(4-methyl-3-nitrophenyl)-4H-pyran-4-one 2. Enamine intermediate in this reaction, 3, reacts with aroyl chlorides in the presence of 1,4-diazabicyclo[2.2.2]octane in dioxane to give the substituted enamines 8(a-c). Enamines 8a,b undergo reductive cyclization with Fe/AcOH to the corresponding 3-aroylindoles 10a,b. |
| File Format | PDF HTM / HTML |
| DOI | 10.1002/chin.200936134 |
| Volume Number | 40 |
| Alternate Webpage(s) | https://asatid.tabrizu.ac.ir/PDF/498_781630c1-5382-4909-9c6f-29531a08d981.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |