NDLI: Costo-efectividad de la vacunación contra Haemophilus influenzae tipo b

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Costo-efectividad de la vacunación contra Haemophilus influenzae tipo b

Content Provider	Semantic Scholar
Author	Carcía, A. Postma, Maarten J. Gálvez, Ana Maria Porcel Sierra, Gustavo
Copyright Year	2002
Abstract	The objective of the present study was to estimate the cost-effectiveness ratio of the therapeutic and prophylactic alternatives for treatment of meningitis caused by Haemophilus influenzae type b in less than one year old infants applying a mathematical model. A hypothetical setting with two alternatives was analyzed: to vaccinate or not to vaccinate. A 100% immunization coverage, as well as a 100% therapeutic coverage for sick persons were considered. The morbidity and lethality rates were taken from data for Cuba during 1998. The costs of the healing treatment and the immunization were calculated from a social perspective. An analysis of cost-effectiveness was modeled using the cost of each life saved as an indicator. For the vaccination alternative the use of conjugated vaccines was considered: Hibtiter (HBOC), Pedvax-Hib (PRP-OMP), Act-Hib (PRP-T) and, for the therapeutic treatment, third generation cephalosporins such as ceftaxidine and ceftriaxone. The unit cost of vaccination was 18.68 pesos for the HBOC and 14.01 pesos for the PRP-T and the PRP-OMP. The unit cost of treatment was 881.19 pesos. The cost-effectiveness ratio for the alternative not to vaccinate was 10.36 pesos for each life saved. For the vaccination alternative the cost-effectiveness ratio was: 0.19, 0.15, 0.20 pesos for each life saved respectively for the vaccines HBOC, PRP-OMP and PRP-T. Vaccination was a cost-effective alternative, the best results being achieved if the cost does not exceed $2.50 per dose with effectiveness values between 100% and 90%.
File Format	PDF HTM / HTML
Volume Number	11
Alternate Webpage(s)	http://scielo.sld.cu/pdf/vac/v11n3/vac01302.pdf
Alternate Webpage(s)	https://www.rug.nl/research/portal/files/52684570/Costo_efectividad_de_la_vacunaci_n.pdf
Alternate Webpage(s)	http://www.bvv.sld.cu/vaccimonitor/vm2002/a7.pdf
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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