Efeito do treinamento com pesos na apatia, funções cognitivas frontais e funcionalidade motora em pacientes com doença de Alzheimer

Content Provider	Semantic Scholar
Author	Hernandez, Soleman Stéphany, Salma
Copyright Year	2011
Abstract	The objectives of this study were: a) characterize the presence of apathy in community dwelling patients with AD; b) analyze the effects of resistance training on apathy, frontal cognitive functions, motor function and metabolic variables of these patients; c) verify possible relations before and after four months of resistance training in apathy, frontal cognitive functions, motor function; and d) verify if there are differences in cognitive and motor function according to the level of apathy of the patients. To do so, participated in the study 28 patients with AD, mean age 78.8 ± 6.6 years, education 4.8 ± 3.5 years who were divided into training group (TG) and group of social interaction (GSI ). All patients were evaluated according to the following tests: Clinical Dementia Rating; Modified Baecke Questionnaire for Elderly; Mini Mental State Examination; Montreal Cognitive Assessment; Semantic Verbal FluencyTest; Clock Drawing Test; Battery Frontal Assessment; Cornell Scale for Depression in dementia; Neuropsychiatric Inventory (domain Apathy); Motor Battery Test of Andreotti O Wells protocol; upper limb strength from AAHPERD battery; Sit and Stand up from a chair in 30 seconds. Besides that, the patients undertook laboratory tests to measure serum levels of total cholesterol and fractions, homocysteine and glucose. The TG participated in a resistance training protocol (RT) for four months, three times a week on nonconsecutive days lasting 60 minutes each session. The training consisted in performing three sets of 20 repetitions, with two minutes between sets and, exercises for major muscle groups. GSI participated in reading, clippings, group dynamics activities and non-systematized mild walking during the same period, frequency and duration of the RT. It was used as statistical analysis ANOVA two way, U Mann Whitney and Wilcoxon tests, and Pearson and Spearman for correlation coefficients, after verifying the data distribution by the Shapiro Wilk test. It was assumed significance level of 5% for all analysis. From the 28 participants, 12 (42.8%) presented apathy symptoms in low level. After the intervention period, the RT was effective on improving upper limb strength, flexibility, reducing serum levels of blood glucose and total cholesterol from the TG. The TP also was effective maintaining the variables: caregiver's report in relation to patients' activities of daily living and serum levels of homocysteine. There were no reasonable relation to the objective of the study. Analyzing the patients according to the level of apathy, the apathetic group had a significant improvement in the symptoms of apathy, verbal fluency test and stand up from the ground when compared to the nonapathetic group, after experimental period.
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Alternate Webpage(s)	https://repositorio.unesp.br/bitstream/handle/11449/87396/solemanhernandez_ss_me_rcla.pdf?isAllowed=y&sequence=1
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article