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Conformational analysis of synthetic androgens. IV. 1,2-seco-A-bisnor-5α-androstan-17β-ol acetate
| Content Provider | Semantic Scholar |
|---|---|
| Author | Rohrer, Douglas C. Duax, William L. Wolff, Manfred E. |
| Copyright Year | 1979 |
| Abstract | Abstract The crystal and molecular structure of 1,2-seco-A-bisnor-5α-androstan-17β-ol acetate has been determined to evaluate the conformational importance of the intact steroid nucleus. The resulting tricyclic compound retains nearly the same steric profile for the remainder of the molecule when compared to the structures of dihydrotestosterone derivatives with intact A-rings. This may help to explain why these types of molecules retain a significant level of androgenic activity. |
| Starting Page | 589 |
| Ending Page | 595 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/S0039-128X(79)80020-3 |
| Volume Number | 34 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/S0039128X79800203 |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/S0039128X79800203?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/S0039-128X%2879%2980020-3 |
| Journal | Steroids |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |